Coexisting elastosis perforans serpiginosa and acquired cutis laxa following long-term penicillamine in Wilson disease

We report a rare case of coexisting elastosis perforans serpiginosa and acquired cutis laxa in a patient with Wilson's disease following prolonged penicillamine therapy. This represents two rare but important dermatologic complications of long-term chelation therapy that clinicians should be aware of, given the potential for underlying elastin disruption to also affect systemic tissues.

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Publication Details

Journal
Skin Health and Disease
Published
2025-08-13
DOI
https://doi.org/10.1093/skinhd/vzaf060
Citations
1
Primary Topic
Dermatological and Skeletal Disorders
Type
article
Field-Weighted Citation Impact
1.82
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article

Coexisting elastosis perforans serpiginosa and acquired cutis laxa following long-term penicillamine in Wilson disease

Nicholas Van Rooij, Taotao Ma
1 citations
Skin Health and Disease
Dermatological and Skeletal Disorders
1.82
article

Coexisting elastosis perforans serpiginosa and acquired cutis laxa following long-term penicillamine in Wilson disease

Nicholas Van Rooij, Taotao Ma
article en
1 citations

Abstract

We report a rare case of coexisting elastosis perforans serpiginosa and acquired cutis laxa in a patient with Wilson's disease following prolonged penicillamine therapy. This represents two rare but important dermatologic complications of long-term chelation therapy that clinicians should be aware of, given the potential for underlying elastin disruption to also affect systemic tissues.

Skin Health and DiseaseVol. 5(6)
Princess Alexandra Hospital (AU), Princess Alexandra Hospital (GB)
Openalex Percentile: Top 13%
Dermatological and Skeletal Disorders
1.82
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