Maternal and Neonatal Outcome of Pregnant Women with Coronavirus (COVID-19) at Mansoura University Hospital

Objective: This study aimed to evaluate maternal and fetal outcome of pregnant women with coronavirus (Covid-19). Methods: This prospective cohort study was conducted on a group of pregnant females diagnosed to have Covid-19. Primary outcomes included maternal mortality rate. Secondary outcomes included gestational age (GA) at time of admission, mode of termination of pregnancy, hospital stay, perioperative complications, neurological complications, post-partum hemorrhage, & puerperal sepsis, and fetal outcomes which included vertical transmission, admission to NICU, APGAR SCORE at 0,5 min and Fetal weight. Results: The presenting symptoms in the females was Cough in 100%, dyspnea in 98.6%, fatigue in 80%, fever in 65.7%, loss of taste in 17.1%, loss of smell in 12.9% and diarrhea in 2.9%. Regarding the computed tomography findings in the included cases, CORAD 2 was reported in 7.1%, CORAD 3 in 38.6%, CORAD 4 in 21.4%, CORAD 5 in 28.6% and CORAD 6 in 4.3%. The reported maternal complications were Lung problems in 8 case, postoperative fever in 2 cases, wound infection in 1 case, deep venous thrombosis (DVT) in 1 case and Pulmonary embolism in 1 case. The mean APGAR score 1 minute was 5.78 ± 2.17. The mean APGAR score 5 minutes was 6 ± 2.06.There were 35 preterm neonates and14 neonates who were admitted into NICU. Conclusion: This study highlighted the significant impact of COVID-19 on pregnant women, with a high rate of cesarean sections, maternal complications, and a21.4% mortality rate. Neonatal outcomes were also affected,with presence of preterm births and NICU admissions.