Innovative Reservoir-Based Drug Delivery Systems for Enhanced Pain Management: A Comprehensive Review of Current Approaches

Reservoir-based drug delivery systems regulate medication release over a specific period, ensuring steady and sustained delivery. They consist of a reservoir holding the drug formulation and a semi-permeable membrane controlling drug diffusion. These systems improve patient adherence, reduce dosing frequency, and allow customized drug release profiles. They are promising in medical applications, particularly for chronic conditions, offering patient-friendly approaches and greater control over drug administration. As a result, these systems provide the advantages of minimal toxicity, high bioavailability, targeted and regulated drug administration, and enhanced therapeutic effectiveness. A major public health concern, pain affects 1.5 billion people worldwide. A trustworthy drug delivery method is still elusive despite efforts to develop novel therapies. A more holistic approach is being adopted by researchers, who are looking for creative ways to reduce the occurrence of pain and its negative repercussions. Millions of people around the world can find relief and hope as the medical profession works to develop innovative approaches to pain treatment. We carried out considerable research on producing reservoir-based drug delivery formulations for chronic pain management. We examined current developments of reservoir-based drug delivery systems for creative approaches to target pain management. We also classify the classes of reservoir-based drug delivery systems and polymer used to produce the reservoir-based drug delivery systems.