Sensorimotor cortical integration remains unchanged after dorsal root ganglion pulsed radiofrequency
DRG PRF effectively reduces pain in chronic radicular pain patients, but its effect on cortical cholinergic modulation, as measured by SAI, appears to be limited. This finding suggests that DRG PRF primarily exerts its effects through non-cholinergic mechanisms, such as GABAergic, glutamatergic, or noradrenergic pathways. Further studies are warranted to clarify the broader neurophysiological effects of DRG PRF.
Authors
- Güngör Enver Özgencil (ORCID: https://orcid.org/0000-0002-9624-9649)
- Ahmet Başarı (ORCID: https://orcid.org/0000-0002-6870-2282)
- Hasan Kılınç (ORCID: https://orcid.org/0000-0001-8825-4475)
- Hanzade Aybüke Ünal
- Bülent Çengiz (ORCID: https://orcid.org/0000-0002-1688-9516)
- Çağrı Cansu
- İlker Burak Arslan (ORCID: https://orcid.org/0000-0003-3933-8327)
Institutions
- Ankara University (TR)
- Institute of Neuroimmunology of the Slovak Academy of Sciences (SK)
- Türk Anesteziyoloji ve Reanimasyon Derneği (TR)
- Gazi University (TR)
Publication Details
- Journal
- Pain Medicine
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1093/pm/pnaf125
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00