Intestinal Mucosal Immune Responses to Novel Oral Poliovirus Vaccine Type 2 in Healthy Newborns
Vaccination with 2 doses of nOPV2 in neonates induced strong intestinal mucosal antibody responses. In cVDPV2 outbreak settings, neonatal administration of nOPV2 may be a strategy to enhance population-level intestinal mucosal immunity.
Authors
- Peter F. Wright (ORCID: https://orcid.org/0000-0003-1950-6928)
- Ananda S Bandyopadhyay (ORCID: https://orcid.org/0000-0002-8395-2001)
- Ruth I. Connor
- Bernardo A. Mainou (ORCID: https://orcid.org/0000-0002-7721-183X)
- Wendy Wieland‐Alter (ORCID: https://orcid.org/0000-0001-9356-8188)
- John F. Modlin (ORCID: https://orcid.org/0000-0003-1391-009X)
- Audrey Godin (ORCID: https://orcid.org/0000-0001-7444-6855)
- Omar M. Sajjad (ORCID: https://orcid.org/0000-0003-0318-9737)
- Joshua A. Weiner (ORCID: https://orcid.org/0000-0003-1054-0628)
- Margaret E. Ackerman (ORCID: https://orcid.org/0000-0002-4253-3476)
- Sohel Rana (ORCID: https://orcid.org/0000-0002-5202-5053)
- Khalequ Zaman (ORCID: https://orcid.org/0000-0002-1982-6879)
- Minetaro Arita (ORCID: https://orcid.org/0000-0002-3314-6626)
- Elizabeth Bailey Brickley (ORCID: https://orcid.org/0000-0003-0280-2288)
- Christopher Gast (ORCID: https://orcid.org/0000-0003-4216-679X)
- Masuma Hoque (ORCID: https://orcid.org/0009-0003-7943-3027)
Institutions
- Dartmouth College (US)
- Dartmouth Institute for Health Policy and Clinical Practice (US)
- Centers for Disease Control and Prevention (US)
- Gates Foundation (US)
- Program for Appropriate Technology in Health (US)
- Colorado School of Public Health (US)
- International Centre for Diarrhoeal Disease Research (BD)
- National Institute of Infectious Diseases (JP)
- London School of Hygiene & Tropical Medicine (GB)
- Dartmouth Psychiatric Research Center (US)
- The Centers (US)
- Center for Global Health (US)
- Dartmouth Health (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1093/cid/ciaf484
- Citations
- 1
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Bill and Melinda Gates Foundation
- Dartmouth College
- International Centre for Diarrhoeal Disease Research, Bangladesh