Intestinal Mucosal Immune Responses to Novel Oral Poliovirus Vaccine Type 2 in Healthy Newborns

Vaccination with 2 doses of nOPV2 in neonates induced strong intestinal mucosal antibody responses. In cVDPV2 outbreak settings, neonatal administration of nOPV2 may be a strategy to enhance population-level intestinal mucosal immunity.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2025-09-03
DOI
https://doi.org/10.1093/cid/ciaf484
Citations
1
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
1.39

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Intestinal Mucosal Immune Responses to Novel Oral Poliovirus Vaccine Type 2 in Healthy Newborns

Peter F. Wright, Ananda S Bandyopadhyay, Ruth I. Connor, Bernardo A. Mainou et al.
1 citations
Clinical Infectious Diseases
Viral Infections and Immunology Research
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article

Intestinal Mucosal Immune Responses to Novel Oral Poliovirus Vaccine Type 2 in Healthy Newborns

Peter F. Wright, Ananda S Bandyopadhyay, Ruth I. Connor, Bernardo A. Mainou, Wendy Wieland‐Alter, John F. Modlin, Audrey Godin, Omar M. Sajjad, Joshua A. Weiner, Margaret E. Ackerman, Sohel Rana, Khalequ Zaman, Minetaro Arita, Elizabeth Bailey Brickley, Christopher Gast, Masuma Hoque
article en
1 citations

Abstract

Vaccination with 2 doses of nOPV2 in neonates induced strong intestinal mucosal antibody responses. In cVDPV2 outbreak settings, neonatal administration of nOPV2 may be a strategy to enhance population-level intestinal mucosal immunity.

Clinical Infectious DiseasesVol. 82(2)
Dartmouth College (US), Dartmouth Institute for Health Policy and Clinical Practice (US), Centers for Disease Control and Prevention (US), Gates Foundation (US), Program for Appropriate Technology in Health (US), Colorado School of Public Health (US), International Centre for Diarrhoeal Disease Research (BD), National Institute of Infectious Diseases (JP), London School of Hygiene & Tropical Medicine (GB), Dartmouth Psychiatric Research Center (US), The Centers (US), Center for Global Health (US), Dartmouth Health (US)
Bill and Melinda Gates Foundation, Dartmouth College, International Centre for Diarrhoeal Disease Research, Bangladesh
Openalex Percentile: Top 15%
Viral Infections and Immunology Research
1.39
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