Downregulation of IFIT3 Relieves the Inflammatory Response in Ulcerative Colitis via Selectively Regulating Macrophage M1 Polarization and the STAT1/2 Signaling Pathway
Our findings highlight the role of IFIT3 in inflammatory responses and macrophage polarization in colitis, suggesting that IFIT3 may be a promising target for UC treatment.
Authors
- Yiran Tao (ORCID: https://orcid.org/0000-0002-8894-5943)
- Meiling Du (ORCID: https://orcid.org/0000-0002-7036-1800)
- Jin Liu (ORCID: https://orcid.org/0000-0002-1388-551X)
- Ke Yang (ORCID: https://orcid.org/0000-0001-6271-8294)
- Xia Yang
Institutions
- Fudan University (CN)
- Community Health Center (US)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/jir.s542033
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00