Kappa Free Light Chain Index in the Real World—Do We Miss Clinically Relevant Information by Skipping Oligoclonal Banding?
κ-FLC index shows high agreement with OCB. Discordant results were largely confined to κ-FLC index between 3.5 and 20 ("gray zone"). A reflex approach, that is, initial screening with κ-FLC index and in case of values within the "gray zone" performing OCB, seems reasonable.
Authors
- Franziska Di Pauli (ORCID: https://orcid.org/0000-0001-6183-2394)
- Harald Hegen
- Michael Auer (ORCID: https://orcid.org/0000-0002-5117-4225)
- Klaus Berek (ORCID: https://orcid.org/0000-0003-2755-2043)
- Martin Schmidauer (ORCID: https://orcid.org/0009-0007-3081-854X)
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1111/ene.70355
- Citations
- 6
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.84