Review on Bio- Analytical Chemistry: A Key to Understanding Biological Molecules

Bio-analytical chemistry plays a crucial role in the quantitative measurement of analytes in biological matrices, supporting drug development, therapeutic monitoring, and disease diagnosis. This field employs a range of methodologies, including chromatography (HPLC, GC), mass spectrometry (LC-MS/MS), and electrophoresis (CE). Ensuring the accuracy and reliability of these methods requires rigorous validation, encompassing assessments of specificity, sensitivity, precision, and stability. As bio-analytical chemistry continues to evolve, advancements in miniaturization, high-throughput analysis, and omics technologies (study large sets of biological molecules) are enhancing its capabilities. The development of precise and dependable analytical methods is essential for driving biomedical research and improving healthcare outcomes. By integrating cutting-edge techniques with robust validation protocols, bio-analytical chemistry remains a vital discipline in the pursuit of scientific and medical advancements.

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Publication Details

Journal
International Journal of Pharmaceutical Research and Applications
Published
2025-04-01
DOI
https://doi.org/10.35629/4494-100411741184
Primary Topic
Various Chemistry Research Topics
Type
article
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article

Review on Bio- Analytical Chemistry: A Key to Understanding Biological Molecules

R. Sıva Subramanıan, Sheela.S Sheela.S, Dr.P.Vaijayanthimala Dr.P.Vaijayanthimala
International Journal of Pharmaceutical Research and Applications
Various Chemistry Research Topics
article

Review on Bio- Analytical Chemistry: A Key to Understanding Biological Molecules

R. Sıva Subramanıan, Sheela.S Sheela.S, Dr.P.Vaijayanthimala Dr.P.Vaijayanthimala
article en

Abstract

Bio-analytical chemistry plays a crucial role in the quantitative measurement of analytes in biological matrices, supporting drug development, therapeutic monitoring, and disease diagnosis. This field employs a range of methodologies, including chromatography (HPLC, GC), mass spectrometry (LC-MS/MS), and electrophoresis (CE). Ensuring the accuracy and reliability of these methods requires rigorous validation, encompassing assessments of specificity, sensitivity, precision, and stability. As bio-analytical chemistry continues to evolve, advancements in miniaturization, high-throughput analysis, and omics technologies (study large sets of biological molecules) are enhancing its capabilities. The development of precise and dependable analytical methods is essential for driving biomedical research and improving healthcare outcomes. By integrating cutting-edge techniques with robust validation protocols, bio-analytical chemistry remains a vital discipline in the pursuit of scientific and medical advancements.

International Journal of Pharmaceutical Research and ApplicationsVol. 10(4)
Openalex Percentile: Top 78%
Various Chemistry Research Topics
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