Five-Year Retrospective Cohort Study of Changes in the International Classification of Functioning, Disability and Health of Children and Youth Parameters in Cerebral Palsy Children and Adolescents With Continuous Intrathecal Baclofen Therapy Versus
Continuous intrathecal baclofen therapy improves structure and function, autonomy, and participation in both short and long term. Overall, the continuous intrathecal baclofen therapy group, with its characteristics of initially greater pain and hypertonia, benefited significantly from the efficacy of intrathecal Baclofen treatment compared with the control group, which continued to receive conventional treatment.The International Classification of Functioning, Disability and Health of Children and Youth outcome measures demonstrated an interrelationship between spasticity and weakness and disease progression over childhood to adolescence.Follow-up will be vital for effective personalized treatment, quality of life, and research.Long-term International Classification of Functioning, Disability and Health of Children and Youth data collection is key to comparing treatment outcomes.
Authors
- Chiara Tacchino (ORCID: https://orcid.org/0000-0002-4338-5356)
- Alessia Aiello (ORCID: https://orcid.org/0000-0002-1616-3096)
- Luca Doglio
- Gianluca Piatelli (ORCID: https://orcid.org/0000-0003-3754-0898)
- Pasquale Cardellicchio (ORCID: https://orcid.org/0000-0003-4628-7177)
- Giulia Biasotti
- Marta Bertamino (ORCID: https://orcid.org/0000-0002-8096-7806)
- Marco Pavanello (ORCID: https://orcid.org/0000-0001-7312-0204)
- Anna Ronchetti (ORCID: https://orcid.org/0000-0002-3291-5075)
- Annalisa Calcagno
- Angela Pistorio
- Paolo Moretti
Institutions
- Istituto Giannina Gaslini (IT)
- Ospedale Policlinico San Martino (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- American Journal of Physical Medicine & Rehabilitation
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1097/phm.0000000000002770
- Primary Topic
- Cerebral Palsy and Movement Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00