Five-Year Retrospective Cohort Study of Changes in the International Classification of Functioning, Disability and Health of Children and Youth Parameters in Cerebral Palsy Children and Adolescents With Continuous Intrathecal Baclofen Therapy Versus

Continuous intrathecal baclofen therapy improves structure and function, autonomy, and participation in both short and long term. Overall, the continuous intrathecal baclofen therapy group, with its characteristics of initially greater pain and hypertonia, benefited significantly from the efficacy of intrathecal Baclofen treatment compared with the control group, which continued to receive conventional treatment.The International Classification of Functioning, Disability and Health of Children and Youth outcome measures demonstrated an interrelationship between spasticity and weakness and disease progression over childhood to adolescence.Follow-up will be vital for effective personalized treatment, quality of life, and research.Long-term International Classification of Functioning, Disability and Health of Children and Youth data collection is key to comparing treatment outcomes.

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Publication Details

Journal
American Journal of Physical Medicine & Rehabilitation
Published
2025-09-01
DOI
https://doi.org/10.1097/phm.0000000000002770
Primary Topic
Cerebral Palsy and Movement Disorders
Type
article
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article

Five-Year Retrospective Cohort Study of Changes in the International Classification of Functioning, Disability and Health of Children and Youth Parameters in Cerebral Palsy Children and Adolescents With Continuous Intrathecal Baclofen Therapy Versus

Chiara Tacchino, Alessia Aiello, Luca Doglio, Gianluca Piatelli et al.
American Journal of Physical Medicine & Rehabilitation
Cerebral Palsy and Movement Disorders
article

Five-Year Retrospective Cohort Study of Changes in the International Classification of Functioning, Disability and Health of Children and Youth Parameters in Cerebral Palsy Children and Adolescents With Continuous Intrathecal Baclofen Therapy Versus

Chiara Tacchino, Alessia Aiello, Luca Doglio, Gianluca Piatelli, Pasquale Cardellicchio, Giulia Biasotti, Marta Bertamino, Marco Pavanello, Anna Ronchetti, Annalisa Calcagno, Angela Pistorio, Paolo Moretti
article en

Abstract

Continuous intrathecal baclofen therapy improves structure and function, autonomy, and participation in both short and long term. Overall, the continuous intrathecal baclofen therapy group, with its characteristics of initially greater pain and hypertonia, benefited significantly from the efficacy of intrathecal Baclofen treatment compared with the control group, which continued to receive conventional treatment.The International Classification of Functioning, Disability and Health of Children and Youth outcome measures demonstrated an interrelationship between spasticity and weakness and disease progression over childhood to adolescence.Follow-up will be vital for effective personalized treatment, quality of life, and research.Long-term International Classification of Functioning, Disability and Health of Children and Youth data collection is key to comparing treatment outcomes.

American Journal of Physical Medicine & RehabilitationVol. 104(12)
Istituto Giannina Gaslini (IT), Ospedale Policlinico San Martino (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Openalex Percentile: Top 72%
Cerebral Palsy and Movement Disorders
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