Sex‐specific pathways from early irritability trajectories to later suicidal ideations and behaviors: Findings from the <scp>ABCD</scp> study®
Distinct trajectories of parent-reported irritability in childhood are differentially associated with suicidal ideation and behavior in adolescence, with the high-stable trajectory conferring the greatest risk. Internalizing and externalizing symptoms play key mediating roles, with notable sex differences in children following rising and declining irritability trajectories. Females with high irritability at any time point in preadolescence were at particular risk for suicidal behaviors.
Authors
- Zeyan Liew (ORCID: https://orcid.org/0000-0002-9424-7869)
- Antonio Simeone (ORCID: https://orcid.org/0000-0003-2693-9836)
- Massimiliano Orri (ORCID: https://orcid.org/0000-0003-1389-2610)
- Nellia Bellaert (ORCID: https://orcid.org/0000-0001-9215-8179)
- Haoran Zhuo (ORCID: https://orcid.org/0000-0001-6514-2585)
- Lanting Zhang
- Wan‐Ling Tseng (ORCID: https://orcid.org/0000-0001-8441-7118)
Institutions
- University of Mons (BE)
- Douglas Mental Health University Institute (CA)
- McGill University Health Centre (CA)
- Yale Cancer Center (US)
- Yale University (US)
- University of Oxford (GB)
- Danish National Centre for Social Research (DK)
- Providence Center (US)
- McGill University (CA)
Publication Details
- Journal
- Journal of Child Psychology and Psychiatry
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1111/jcpp.70044
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Belgian American Educational Foundation
- Charles H. Hood Foundation
- Fonds De La Recherche Scientifique - FNRS
- National Institute of Mental Health
- Yale Center for Clinical Investigation, Yale School of Medicine