Enhancing Diagnostic Quality in Panoramic Radiography: A Comparative Evaluation of GAN Models for Image Restoration

ABSTRACT Panoramic imaging is a widely utilized technique to capture a comprehensive view of the maxillary and mandibular dental arches and supporting facial structures. This study evaluates the potential of the Generative Adversarial Network (GAN) models—Pix2Pix, CycleGAN, and RegGAN—in enhancing diagnostic quality by addressing combinations of common image distortions. A panoramic radiograph data set was processed to simulate four types of distortions: (i) blurriness, (ii) noise, (iii) combined blurriness and noise, and (iv) anterior‐region‐specific blurriness. Three GAN models were trained and analyzed using quantitative metrics such as the peak signal‐to‐noise ratio (PSNR) and the structural similarity index measure (SSIM). In addition, two oral and maxillofacial radiologists conducted qualitative reviews to assess the diagnostic reliability of the generated images. Pix2Pix consistently outperformed CycleGAN and RegGAN, achieving the highest PSNR and SSIM values across all types of distortions. Expert evaluations also favored Pix2Pix, highlighting its ability to restore image accuracy and enhance clinical utility. CycleGAN showed moderate improvements in noise‐affected images but struggled with combined distortions, while RegGAN yielded negligible enhancements. These findings underscore its potential for clinical application in refining radiographic imaging. Future research should focus on combining GAN techniques and utilizing larger datasets to develop universally robust image enhancement models.