A Report on the Use of Biparametric MRI in Prostate Cancer Diagnosis: A Two-Year Single Centre Experience

The average age of the study population was 69.7±7.3 years, with the majority of the patients above 70 years. A statistically significant positive correlation was observed between PSAD and Prostate Imaging-Reporting and Data System (PI-RADS) scores (r=0.2, p<0.001). Higher PSAD groups showed an increased proportion of PI-RADS 4 and 5 lesions. There was a significant positive correlation (r=0.2, p<0.001) between PSAD and International Society of Urological Pathology (ISUP) grade, indicating that the detection of clinically significant and higher-grade prostate cancer increases with PSAD. High-risk prostate cancers (ISUP grades 4 and 5) were detected in the high-risk category of PSAD (14.6% and 18%, respectively). PI-RADS scores correlated significantly with ISUP grades (r=0.3, p<0.001). Conclusion: Our study demonstrated that bpMRI-detected PI-RADS scores significantly correlated with PSAD, histological diagnosis (ISUP grade), and clinically significant prostate cancer detection. bpMRI has a role in the diagnostic value of prostate cancer when combined with PSAD and a family history of prostate cancer. It is effective in detecting clinically significant prostate cancers at a lower cost and shorter time while eliminating the potential harm of the use of gadolinium.

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Publication Details

Journal
Cureus
Published
2025-09-04
DOI
https://doi.org/10.7759/cureus.91630
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

A Report on the Use of Biparametric MRI in Prostate Cancer Diagnosis: A Two-Year Single Centre Experience

Alfian Fahmy, Maya Harris, Jane Anderson, Andrea Ginepri et al.
1 links
Cureus
Prostate Cancer Diagnosis and Treatment
article

A Report on the Use of Biparametric MRI in Prostate Cancer Diagnosis: A Two-Year Single Centre Experience

Alfian Fahmy, Maya Harris, Jane Anderson, Andrea Ginepri, Tolulope Taiwo Ogunfowora, Khaled Bseikri, Adnan Malik, Rahim Kaba, Amr Mohamed, Amman Malik, Quadri A Sanni, Sadiq Abu, James Tsejime, Rajasekaran Siddhan
article en

Abstract

The average age of the study population was 69.7±7.3 years, with the majority of the patients above 70 years. A statistically significant positive correlation was observed between PSAD and Prostate Imaging-Reporting and Data System (PI-RADS) scores (r=0.2, p<0.001). Higher PSAD groups showed an increased proportion of PI-RADS 4 and 5 lesions. There was a significant positive correlation (r=0.2, p<0.001) between PSAD and International Society of Urological Pathology (ISUP) grade, indicating that the detection of clinically significant and higher-grade prostate cancer increases with PSAD. High-risk prostate cancers (ISUP grades 4 and 5) were detected in the high-risk category of PSAD (14.6% and 18%, respectively). PI-RADS scores correlated significantly with ISUP grades (r=0.3, p<0.001). Conclusion: Our study demonstrated that bpMRI-detected PI-RADS scores significantly correlated with PSAD, histological diagnosis (ISUP grade), and clinically significant prostate cancer detection. bpMRI has a role in the diagnostic value of prostate cancer when combined with PSAD and a family history of prostate cancer. It is effective in detecting clinically significant prostate cancers at a lower cost and shorter time while eliminating the potential harm of the use of gadolinium.

CureusVol. 17(9)
Sandwell & West Birmingham Hospitals NHS Trust (GB), Glenfield Hospital (GB), South Warwickshire NHS Foundation Trust (GB)
Openalex Percentile: Top 65%
Prostate Cancer Diagnosis and Treatment
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