A Report on the Use of Biparametric MRI in Prostate Cancer Diagnosis: A Two-Year Single Centre Experience
The average age of the study population was 69.7±7.3 years, with the majority of the patients above 70 years. A statistically significant positive correlation was observed between PSAD and Prostate Imaging-Reporting and Data System (PI-RADS) scores (r=0.2, p<0.001). Higher PSAD groups showed an increased proportion of PI-RADS 4 and 5 lesions. There was a significant positive correlation (r=0.2, p<0.001) between PSAD and International Society of Urological Pathology (ISUP) grade, indicating that the detection of clinically significant and higher-grade prostate cancer increases with PSAD. High-risk prostate cancers (ISUP grades 4 and 5) were detected in the high-risk category of PSAD (14.6% and 18%, respectively). PI-RADS scores correlated significantly with ISUP grades (r=0.3, p<0.001). Conclusion: Our study demonstrated that bpMRI-detected PI-RADS scores significantly correlated with PSAD, histological diagnosis (ISUP grade), and clinically significant prostate cancer detection. bpMRI has a role in the diagnostic value of prostate cancer when combined with PSAD and a family history of prostate cancer. It is effective in detecting clinically significant prostate cancers at a lower cost and shorter time while eliminating the potential harm of the use of gadolinium.
Authors
- Alfian Fahmy
- Maya Harris (ORCID: https://orcid.org/0000-0003-1165-1506)
- Jane Anderson (ORCID: https://orcid.org/0000-0001-5294-8707)
- Andrea Ginepri
- Tolulope Taiwo Ogunfowora
- Khaled Bseikri
- Adnan Malik
- Rahim Kaba (ORCID: https://orcid.org/0000-0003-2026-0339)
- Amr Mohamed (ORCID: https://orcid.org/0000-0003-1547-5941)
- Amman Malik
- Quadri A Sanni (ORCID: https://orcid.org/0000-0002-0930-3636)
- Sadiq Abu (ORCID: https://orcid.org/0000-0001-7447-7547)
- James Tsejime
- Rajasekaran Siddhan
Institutions
- Sandwell & West Birmingham Hospitals NHS Trust (GB)
- Glenfield Hospital (GB)
- South Warwickshire NHS Foundation Trust (GB)
Publication Details
- Journal
- Cureus
- Published
- 2025-09-04
- DOI
- https://doi.org/10.7759/cureus.91630
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00