Therapeutic Potential of Cannabis Plant in Diabetes

Abstract: Diabetes mellitus (DM) is a metabolic disorder of the endocrine system that poses a serious threat to human health. Although many chemical substances are available for the prevention and treatment of DM and its complications, an optimal treatment for diabetes is not yet available. As an alternative to these synthetic substances, plants are widely used in various traditional medicine systems for the prevention of diabetes. Cannabis sativa L., a member of the Cannabaceae family, is one of the plants with very ancient medicinal use. More than 100 phytocannabinoids have been identified in C. sativa, most notably Δ9-tetrahydrocannabinol and cannabidiol. In addition to cannabinoids, cannabis also contains terpenoids and flavonoids. Various studies have shown that these compounds have many therapeutic effects such as antioxidant, analgesic, immunomodulatory, and anticonvulsant. This review provides an overview of the therapeutic effects of the cannabis plant and its constituents on diabetes and its complications.Cite this article as: Yazıcı Coşkun ZM & Sezekler I. Therapeutic potential of cannabisplant in diabetes. Trends in Pharmacy, 2025, 2, 0005, doi: 10.5152/ TrendsPharm.2025.25005.