Exosome from adipose-derived stromal vascular fraction enhances the proliferation of human dental pulp stem cells

Isolated AD-SVF exosomes, averaging 103 ± 24 nm, expressed CD9+ and CD63+ markers. The study revealed increased hDPSC proliferation on the 5<sup>th</sup> day post low-exosome treatment, indicating a positive association between AD-SVF exosomes and cell proliferation. These results highlight the potential of AD-SVF exosomes to enhance hDPSC proliferation for dental pulp and broader tissue regeneration.

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Publication Details

Journal
Journal of Conservative Dentistry and Endodontics
Published
2025-09-01
DOI
https://doi.org/10.4103/jcde.jcde_427_25
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Exosome from adipose-derived stromal vascular fraction enhances the proliferation of human dental pulp stem cells

Anggraini Margono, Dini Asrianti Bagio, Sylva Dinie Alinda, Indah Julianto
Journal of Conservative Dentistry and Endodontics
Extracellular vesicles in disease
article

Exosome from adipose-derived stromal vascular fraction enhances the proliferation of human dental pulp stem cells

Anggraini Margono, Dini Asrianti Bagio, Sylva Dinie Alinda, Indah Julianto
article en

Abstract

Isolated AD-SVF exosomes, averaging 103 ± 24 nm, expressed CD9+ and CD63+ markers. The study revealed increased hDPSC proliferation on the 5<sup>th</sup> day post low-exosome treatment, indicating a positive association between AD-SVF exosomes and cell proliferation. These results highlight the potential of AD-SVF exosomes to enhance hDPSC proliferation for dental pulp and broader tissue regeneration.

Journal of Conservative Dentistry and EndodonticsVol. 28(9)
Sebelas Maret University (ID), University of Indonesia (ID)
Openalex Percentile: Top 79%
Extracellular vesicles in disease
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Exosome from adipose-derived stromal vascular fraction enhances the proliferation of human dental pulp stem cells — Anggraini Margono, Dini Asrianti Bagio, et al. · Journal of Conservative Dentistry and Endodontics (2025) | TGRS Research Map | TGRS