Mass spectrometry for clinical bioanalysis without chromatographic separation: bioequivalence for bupropion and its metabolites
The results of this study indicate that the HT-SPE-MS/MS system shows potential for high-throughput in vivo bioanalysis, particularly in bioavailability and bioequivalence studies.
Authors
- Patrick J. Faustino (ORCID: https://orcid.org/0000-0002-7719-0813)
- Jinhui Zhang (ORCID: https://orcid.org/0000-0002-1598-815X)
Institutions
- Food and Drug Administration (TH)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1080/17576180.2025.2557187
- Primary Topic
- Biosimilars and Bioanalytical Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00