Suboptimal management of hypercholesterolemia in countries with high or very high cardiovascular risk: findings from the international DISCOVERY study
The DISCOVERY study reveals suboptimal LDL-C control and low adherence to the 2019 ESC/EAS guidelines in routine practice across countries with high/very high CV risk. These findings highlight the urgent need for strategies to improve physician awareness, promote intensive LLT use, and close the gap between guidelines and clinical practice. A paradigm shift toward proactive LDL-C management is essential to reduce residual CV risk in these populations.
Authors
- Gani Bajraktari (ORCID: https://orcid.org/0000-0003-0410-968X)
- Alexandru Caraus
- Hristo Pejkov (ORCID: https://orcid.org/0000-0003-4957-020X)
- Tamara Kovačević-Preradović (ORCID: https://orcid.org/0000-0002-7100-5189)
- Mišo Šabović (ORCID: https://orcid.org/0000-0003-4099-6271)
- Zaim Jatić (ORCID: https://orcid.org/0000-0002-5288-7745)
- I Gruev
- V. Vintila (ORCID: https://orcid.org/0009-0005-6386-7896)
- Zumreta Kušljugić (ORCID: https://orcid.org/0000-0002-8565-776X)
- Zoltán Csanádi (ORCID: https://orcid.org/0000-0002-9720-7256)
- Sodgerel Batjargal
- Draško Kuprešak
Institutions
- University of Sarajevo (BA)
- University of Debrecen (HU)
- University of Ljubljana (SI)
- Carol Davila University of Medicine and Pharmacy (RO)
- Ljubljana University Medical Centre (SI)
- Mongolian National University of Medical Sciences (MN)
- School Centre Celje (SI)
- National Transport Hospital "Tzar Boris III" (BG)
- Institute of Applied Physics (MD)
- University Clinical Center Tuzla (BA)
- Institute of Chemistry (MD)
- University clinical center of Republika Srpska (BA)
- Ss. Cyril and Methodius University in Skopje (MK)
- University of Prishtina (XK)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-09-05
- DOI
- https://doi.org/10.3389/fcvm.2025.1665059
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00