Hierarchical Multiattention Temporal Fusion Network for Dual-Task Atrial Fibrillation Subtyping and Early Risk Prediction

Atrial fibrillation (AF) is a common arrhythmia associated with major adverse cardiovascular events. Early detection and short-horizon risk prediction are therefore clinically critical. Prior attention-based electrocardiogram (ECG) models typically treated subtype classification and short-horizon onset risk prediction as separate tasks and optimized attention in only one representational dimension rather than in a coordinated hierarchy. We propose a hierarchical multiattention temporal fusion network (HMA-TFN). The proposed framework jointly integrates lead-level, morphology-level, and rhythm-level attention, enabling the model to simultaneously highlight diagnostically informative leads, capture waveform abnormalities, and characterize long-range temporal dependencies. Moreover, the model is trained for dual tasks—AF subtype classification and 30-min onset prediction. Experiments were conducted on three open-source databases and the Fuzhou University–Fujian Provincial Hospital (FZU-FPH) clinical database, comprising thousands of dual-lead ECG recordings from a diverse subject population. Experimental results show that HMA-TFN achieves 95.77% accuracy in classifying paroxysmal AF (PAAF) and persistent AF (PEAF), and 96.36% accuracy in predicting PAAF occurrence 30 min in advance. Ablations show monotonic gains as each attention level is added, delivering 14.0% accuracy over the baseline for subtyping and 5.2% for prediction. Grad-CAM visualization highlights clinically relevant features such as absent P-waves, confirming model interpretability. On the FZU-FPH clinical database, it achieves a generalization performance of 94.31%, demonstrating its strong potential for clinical application.

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Publication Details

Journal
Mathematics
Published
2025-09-05
DOI
https://doi.org/10.3390/math13172872
Citations
2
Primary Topic
ECG Monitoring and Analysis
Type
article
Field-Weighted Citation Impact
2.78

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article

Hierarchical Multiattention Temporal Fusion Network for Dual-Task Atrial Fibrillation Subtyping and Early Risk Prediction

Tsung‐Yi Chen, Patricia Angela R. Abu, Shih‐Lun Chen, Bingjie Cai et al.
2 citations
Mathematics
ECG Monitoring and Analysis
2.78
article

Hierarchical Multiattention Temporal Fusion Network for Dual-Task Atrial Fibrillation Subtyping and Early Risk Prediction

Tsung‐Yi Chen, Patricia Angela R. Abu, Shih‐Lun Chen, Bingjie Cai, Liang-Hung Wang, Chao-Xin Xie, Chiung-An Chen, Zne-Jung Lee, Tao Yang, Jiawen Wang
article en
2 citations

Abstract

Atrial fibrillation (AF) is a common arrhythmia associated with major adverse cardiovascular events. Early detection and short-horizon risk prediction are therefore clinically critical. Prior attention-based electrocardiogram (ECG) models typically treated subtype classification and short-horizon onset risk prediction as separate tasks and optimized attention in only one representational dimension rather than in a coordinated hierarchy. We propose a hierarchical multiattention temporal fusion network (HMA-TFN). The proposed framework jointly integrates lead-level, morphology-level, and rhythm-level attention, enabling the model to simultaneously highlight diagnostically informative leads, capture waveform abnormalities, and characterize long-range temporal dependencies. Moreover, the model is trained for dual tasks—AF subtype classification and 30-min onset prediction. Experiments were conducted on three open-source databases and the Fuzhou University–Fujian Provincial Hospital (FZU-FPH) clinical database, comprising thousands of dual-lead ECG recordings from a diverse subject population. Experimental results show that HMA-TFN achieves 95.77% accuracy in classifying paroxysmal AF (PAAF) and persistent AF (PEAF), and 96.36% accuracy in predicting PAAF occurrence 30 min in advance. Ablations show monotonic gains as each attention level is added, delivering 14.0% accuracy over the baseline for subtyping and 5.2% for prediction. Grad-CAM visualization highlights clinically relevant features such as absent P-waves, confirming model interpretability. On the FZU-FPH clinical database, it achieves a generalization performance of 94.31%, demonstrating its strong potential for clinical application.

MathematicsVol. 13(17)
Ming Chi University of Technology (TW), Chung Yuan Christian University (TW), Ateneo de Manila University (PH), Feng Chia University (TW), Fuzhou University (CN)
National Natural Science Foundation of China, Fuzhou University
Openalex Percentile: Top 8%
ECG Monitoring and Analysis
2.78
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