TLR5 influences the development of type 1 diabetes
In the present study, we find a low expression of mRNA for <i>TLR5</i> in patients with newly diagnosed T1D associated with enhanced T cell infiltration. T cells are important for autoimmune diseases, including T1D. We hope that the present findings may be influential for the understanding of how T1D develops.
Authors
- Camilla Hartmann Friis Hansen (ORCID: https://orcid.org/0000-0002-1860-385X)
- Ivan Gerling (ORCID: https://orcid.org/0000-0001-5097-6050)
- Knut Dahl‐Jørgensen (ORCID: https://orcid.org/0000-0002-6952-9899)
- Flemming Pociot (ORCID: https://orcid.org/0000-0003-3274-5448)
- Karsten Buschard (ORCID: https://orcid.org/0000-0002-0126-7423)
- Lars Krogvold (ORCID: https://orcid.org/0000-0002-1057-7095)
- Rikke Thea
Institutions
- University of Copenhagen (DK)
- Oslo University Hospital (NO)
- Steno Diabetes Centers (DK)
- University of Tennessee Health Science Center (US)
- University of Oslo (NO)
- Frederiksberg Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- BMJ Open Diabetes Research & Care
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1136/bmjdrc-2025-005111
- Citations
- 1
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.82