Case Report: Use of extracorporeal support to treat a fulminant Mycobacterium bovis infection and complex broncho-oesophageal fistula in a child
Tuberculosis (TB), caused by <i>Mycobacterium tuberculosis</i> remains a significant public health issue. Human TB caused by <i>Mycobacterium bovis (M. bovis) is rare</i> accounting for less than 1% of TB cases in UK annually. Tuberculosis secondary to immunomodulating agents is well described. We present a case of airway and pulmonary TB caused by <i>M. bovis</i>, likely due to zoonotic transmission, in an immunocompromised child due to medical management of Crohn's disease. Management required extracorporeal membrane oxygenation for complex surgical interventions on airway and oesophagus.
Authors
- Nagarajan Muthialu (ORCID: https://orcid.org/0000-0002-0410-0776)
- Hussein Hussein (ORCID: https://orcid.org/0000-0002-8417-3835)
- Alasdair Bamford (ORCID: https://orcid.org/0000-0003-4764-229X)
- Arun Beeman (ORCID: https://orcid.org/0000-0001-9858-761X)
- Louis Grandjean (ORCID: https://orcid.org/0000-0002-1457-8327)
- Pooja Shetty (ORCID: https://orcid.org/0000-0002-0498-4364)
- Ashwin Pandey
- Katy Fidler (ORCID: https://orcid.org/0000-0001-6947-5205)
- R Paget
- Claire Snowden
Institutions
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- University Hospitals Sussex NHS Foundation Trust (GB)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-09-05
- DOI
- https://doi.org/10.3389/fped.2025.1559240
- Citations
- 1
- Primary Topic
- Esophageal and GI Pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.01