B cell dysregulation during acute COVID-19 is transient
The circulating B cell and Th cell subpopulations experience transitional changes during SARS-CoV-2 infection, but these changes recover in follow-up. EBV and HHV-6B reactivations are common in inpatients, but they are not associated with persisting anosmia.
Authors
- Đỗ Ngọc Ánh (ORCID: https://orcid.org/0000-0001-6086-7659)
- Olli Vapalahti (ORCID: https://orcid.org/0000-0003-2270-6824)
- Nelli Heikkilä (ORCID: https://orcid.org/0000-0002-8879-1569)
- Promio Charles F (ORCID: https://orcid.org/0000-0001-9914-6533)
- Jussi Hepojoki (ORCID: https://orcid.org/0000-0001-5699-214X)
- Tomas Strandin (ORCID: https://orcid.org/0000-0002-2454-7479)
- Xiaobo Huang (ORCID: https://orcid.org/0000-0001-7516-8842)
- Anu Kantele
- Suvi T. Jokiranta (ORCID: https://orcid.org/0000-0003-4988-185X)
- Nowlan Kirsten (ORCID: https://orcid.org/0000-0002-8713-4823)
- Kekäläinen Eliisa
- Santtu Heinonen (ORCID: https://orcid.org/0000-0002-1666-1933)
- Laakso Sini M
- Leo Hannolainen (ORCID: https://orcid.org/0009-0005-5982-413X)
- Pyöriä Lari (ORCID: https://orcid.org/0000-0001-9504-5807)
- Pirkka T. Pekkarinen (ORCID: https://orcid.org/0000-0002-8203-3409)
- Pia Dürnsteiner
- Tinja Lääveri (ORCID: https://orcid.org/0000-0003-4124-6667)
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Aalto University (FI)
Publication Details
- Journal
- Immunology Letters
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1016/j.imlet.2025.107086
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Suomen Lääketieteen Säätiö
- Suomen Kulttuurirahasto
- Biomedicum Helsinki-säätiö
- Orionin Tutkimussäätiö
- Paulon Säätiö