Miltirone attenuates post-ischemic stroke neuroinflammation and microglial lipid metabolism via regulating LBP and TLR4/NF-κB Axis

Miltirone confers neuroprotection through multi-target actions. It simultaneously provides neuroinflammation, regulates lipid metabolism, and counters oxidative stress. This occurs via LBP/TLR4/NF-κB axis modulation. Its multitarget action addresses the complexity of ischemic stroke pathophysiology, positioning it as a promising therapeutic candidate for clinical translation.