Serum albumin demonstrates comparable or superior prognostic value compared to albumin-based ratios in sepsis
Serum albumin is a strong, independent predictor of 30-day mortality in patients with sepsis and outperforms multiple albumin-based ratios in both statistical and clinical utility. Its use in early risk stratification should be encouraged in clinical practice. Further multicenter studies are warranted to confirm these findings and explore their generalizability.
Authors
- Fabrizio Lucente
- Lorenzo Ghiadoni (ORCID: https://orcid.org/0000-0002-7399-2720)
- Mario Maggi (ORCID: https://orcid.org/0000-0003-3267-4221)
- Christian J. Wiedermann (ORCID: https://orcid.org/0000-0002-4639-8195)
- Alessandro Cipriano (ORCID: https://orcid.org/0000-0001-7085-3621)
- Massimo Marchetti
- Arian Zaboli (ORCID: https://orcid.org/0000-0002-4204-8884)
- Gloria Brigiari (ORCID: https://orcid.org/0009-0000-7274-4373)
- Paolo Ferretto
- Gianni Turcato
- Lucia Filippi
Institutions
- University of Pisa (IT)
- MGH Institute of Health Professions (US)
- Institute of Public Health (AL)
- Saint Camillus International University of Health and Medical Sciences (IT)
- Faculty of Public Health (GB)
- Azienda Ospedaliera Universitaria Pisana (IT)
Publication Details
- Journal
- Current Medical Research and Opinion
- Published
- 2025-08-03
- DOI
- https://doi.org/10.1080/03007995.2025.2558128
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35