WDWorm: A runtime-efficient and user-friendly GUI-based toolbox for experimenting with the nerve net of C. elegans

Nerve net simulators of C. elegans heavily support research of its nerve net functionality by offering the possibility to conduct digital experiments instead of real ones. However, current software tools are complex and difficult to use for non-programmers. With WDWorm, we offer a user-friendly toolbox with graphical user interface for simulating and experimenting with C. elegans’ nerve net. It does not require an installation and allows for several modifications of the nerve net, including parameter changes of each neuron and connection or the deactivation of individual neurons. Furthermore, a comparison with other software tools highlights that WDWorm is currently the most runtime-efficient approach for simulating and digitally experimenting with C. elegans . To invite other developers and researchers, we provide the source code in an open-access format under a CC-BY 4.0 Creative Commons license. The code is publicly available at https://github.com/dsacri/WDWorm .

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Publication Details

Journal
Neurocomputing
Published
2025-09-05
DOI
https://doi.org/10.1016/j.neucom.2025.131464
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
Field-Weighted Citation Impact
0.00

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article

WDWorm: A runtime-efficient and user-friendly GUI-based toolbox for experimenting with the nerve net of C. elegans

Karlheinz Ochs, Sebastian Jenderny, Daniel Sacristán, Christian Albers et al.
Neurocomputing
Genetics, Aging, and Longevity in Model Organisms
article

WDWorm: A runtime-efficient and user-friendly GUI-based toolbox for experimenting with the nerve net of C. elegans

Karlheinz Ochs, Sebastian Jenderny, Daniel Sacristán, Christian Albers, Isabella Beyer, Philipp Hövel
article en

Abstract

Nerve net simulators of C. elegans heavily support research of its nerve net functionality by offering the possibility to conduct digital experiments instead of real ones. However, current software tools are complex and difficult to use for non-programmers. With WDWorm, we offer a user-friendly toolbox with graphical user interface for simulating and experimenting with C. elegans’ nerve net. It does not require an installation and allows for several modifications of the nerve net, including parameter changes of each neuron and connection or the deactivation of individual neurons. Furthermore, a comparison with other software tools highlights that WDWorm is currently the most runtime-efficient approach for simulating and digitally experimenting with C. elegans . To invite other developers and researchers, we provide the source code in an open-access format under a CC-BY 4.0 Creative Commons license. The code is publicly available at https://github.com/dsacri/WDWorm .

NeurocomputingVol. 656
Technical University of Applied Sciences Lübeck (DE), Ruhr University Bochum (DE), Saarland University (DE)
Deutsche Forschungsgemeinschaft
Openalex Percentile: Top 80%
Genetics, Aging, and Longevity in Model Organisms
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