Extended oral antibiotics fail to reduce surgical site infection in orthopedic surgeries: A comparative study

Our findings demonstrated that extended oral antibiotics did not reduce the rate of SSI following orthopedic surgeries compared to short-term prophylaxis. Furthermore, patients who received prolonged antibiotic demonstrated a higher incidence of postoperative complications. Our study supports the recommendation not to use extended prophylactic oral antibiotics over 24 hours in orthopedic surgeries.