Alzheimer Disease Biomarkers and Subjective Cognitive Decline Among Hispanic and/or Latino Adults
In this study of middle-aged and older Hispanic and/or Latino adults, plasma biomarkers of p-tau181, NfL, and GFAP, but not Aβ42/40, were associated with greater SCD. These findings underscore their potential utility in early ADRD detection strategies.
Authors
- Freddie Márquez (ORCID: https://orcid.org/0000-0001-9916-9225)
- Zachary T. Goodman (ORCID: https://orcid.org/0000-0002-0126-4425)
- Daniela Sotres‐Alvarez (ORCID: https://orcid.org/0000-0002-3226-6140)
- Bharat Thyagarajan (ORCID: https://orcid.org/0000-0001-6968-6985)
- Amber Pirzada (ORCID: https://orcid.org/0000-0003-0526-3611)
- Linda C. Gallo (ORCID: https://orcid.org/0000-0002-3678-5888)
- Wassim Tarraf (ORCID: https://orcid.org/0000-0001-8888-7918)
- Héctor M. González (ORCID: https://orcid.org/0000-0001-8711-2627)
- Bonnie Levin (ORCID: https://orcid.org/0000-0003-0931-296X)
- Natasha Z. Anita (ORCID: https://orcid.org/0009-0007-9179-1539)
- Michael A. Yassa (ORCID: https://orcid.org/0000-0002-8635-1498)
- Ariana M. Stickel (ORCID: https://orcid.org/0000-0002-6312-2377)
- Kevin A. González (ORCID: https://orcid.org/0000-0002-8958-3884)
- Haibo Zhou (ORCID: https://orcid.org/0000-0002-2468-0093)
- Martha L. Daviglus (ORCID: https://orcid.org/0000-0002-6791-8727)
- Deisha F. Valencia
Institutions
- University of North Carolina at Chapel Hill (US)
- University of Minnesota (US)
- University of Miami (US)
- Wayne State University (US)
- University of California, Irvine (US)
- San Diego State University (US)
- Rehabilitation Institute of Michigan (US)
- University of California San Diego (US)
- University of Illinois Chicago (US)
- Office of Minority Health (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.31038
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Office of Dietary Supplements
- University of Miami
- Northwestern University
- San Diego State University
- Institut National Du Cancer
- National Institutes of Health
- University of Illinois at Urbana-Champaign
- University of California, San Diego
- National Heart, Lung, and Blood Institute
- National Cancer Institute
- National Institute on Deafness and Other Communication Disorders
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute on Minority Health and Health Disparities