Stopping versus continuing renin-angiotensin system inhibitors before surgery: An updated systematic review and meta-analysis of randomised controlled trials
Stopping RASIs in patients undergoing surgery was not associated with a higher risk of postoperative complications, such as MACE, all-cause mortality, myocardial infarction, heart failure/acute pulmonary oedema, stroke, or AKI. Conversely, discontinuing RASIs notably reduced the incidence of intraoperative hypotension.
Authors
- Ahmed Dheyaa Al‐Obaidi
- Hashim Talib Hashim (ORCID: https://orcid.org/0000-0001-6155-7302)
- Omar N. Saab (ORCID: https://orcid.org/0000-0002-9097-5121)
- Alhareth Al-Sagban
- Bashar Al Hemyari (ORCID: https://orcid.org/0000-0001-8248-4632)
- Mohanad Albayyaa (ORCID: https://orcid.org/0000-0003-4185-5294)
- Marwah Algodi
Institutions
- Texas Medical Center (US)
- University of Baghdad (IQ)
- Johns Hopkins University (US)
- Thi Qar University (IQ)
- Johns Hopkins Medicine (US)
- Johns Hopkins University Applied Physics Laboratory (US)
- Jersey Shore University Medical Center (US)
- The University of Texas Medical Branch at Galveston (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Indian Journal of Anaesthesia
- Published
- 2025-09-05
- DOI
- https://doi.org/10.4103/ija.ija_416_25
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00