The Role of Sex in Clinical Characteristics and Pharmacological Treatment of Bipolar Disorder
Taken together, we found fewer differences than expected, which suggests that factors other than sex play a greater role in the course of bipolar disorder. Our analysis indicates that more women are suffering from obsessive-compulsive disorder (OCD) as comorbidity than men, a topic that has not yet been extensively researched. While previous studies mostly show that men have an earlier onset of symptoms, we found the opposite in our sample. Another notable difference in illness course was that men experienced more manic episodes per year. Further research in this area is needed to verify our findings, ideally focusing specifically on OCD in bipolar men and women, as sex differences in this comorbidity remain underexplored.
Authors
- Tatjana Maria Stross (ORCID: https://orcid.org/0000-0002-0442-5319)
- Alfred Häussl (ORCID: https://orcid.org/0000-0001-9623-8707)
- Alexander Maget
- Adelina Tmava‐Berisha (ORCID: https://orcid.org/0000-0002-5068-5947)
- Susanne Bengesser (ORCID: https://orcid.org/0000-0001-8012-908X)
- Melanie Lenger (ORCID: https://orcid.org/0000-0003-0638-5389)
- Robert Queissner (ORCID: https://orcid.org/0000-0001-6632-0902)
- Frederike T. Fellendorf (ORCID: https://orcid.org/0000-0001-7215-3848)
- Elena Schönthaler (ORCID: https://orcid.org/0000-0002-9645-4503)
- Eva Z. Reininghaus (ORCID: https://orcid.org/0000-0001-5964-4087)
- Alexander Finner (ORCID: https://orcid.org/0009-0003-1586-3087)
- Nina Dalkner (ORCID: https://orcid.org/0000-0002-4419-3524)
- Jelena Ilić
- Erik Putz
Institutions
- Medical University of Graz (AT)
Publication Details
- Journal
- Neuropsychobiology
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1159/000548338
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00