Case Series and Literature Review on Phenotypic Variants of Restless Legs Syndrome (RLS): A Unique Phase of Typical RLS?
The clinical features and dopaminergic responsiveness of variant RLS closely resembled those of typical RLS, suggesting that existing diagnostic criteria and treatment strategies for typical RLS is applicable to variant phenotypes. Additionally, the PLMI may indicate the potential for variant RLS symptoms progressing to involvement of the legs.
Authors
- Junying Zhou (ORCID: https://orcid.org/0000-0001-5060-3879)
- Jiafeng Ren (ORCID: https://orcid.org/0000-0002-4663-8187)
- Xinyan Zhang (ORCID: https://orcid.org/0000-0002-7430-0028)
- Yangyang Shen
- Xue Zhou (ORCID: https://orcid.org/0009-0005-5993-8559)
- Weifang Yin
- Haiyi Mi
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Nature and Science of Sleep
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/nss.s528340
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China