The Influence of Vasopressor-Induced Arterial Blood Pressure Elevation on Muscle-Recorded Motor Evoked Potentials
Elevation of MAP is associated with significantly higher Tc-mMEP amplitudes, AUCs, and lower voltage threshold. When corrected for BIS, propofol concentration, and use of ephedrine, the associations between increasing MAP and Tc-mMEP characteristics were largely attenuated. BIS values significantly increased by increasing MAP, when corrected for propofol concentration. Thereby, our results imply that increasing MAP increases the cortical excitability.
Authors
- Rob J. M. Groen (ORCID: https://orcid.org/0000-0003-3067-763X)
- Katalin Tamási (ORCID: https://orcid.org/0000-0001-9391-4597)
- Bianca M. Dijkstra (ORCID: https://orcid.org/0000-0001-6802-7021)
- Marko Sahinovic (ORCID: https://orcid.org/0000-0002-5595-0375)
- Sebastiaan E. Dulfer (ORCID: https://orcid.org/0000-0002-6772-2927)
- Gea Drost (ORCID: https://orcid.org/0000-0002-3546-4548)
- Anthony Ray Absalom (ORCID: https://orcid.org/0000-0001-7563-9157)
- Lilian M. Mennink (ORCID: https://orcid.org/0000-0001-8494-6503)
- Fiete Lange
- Christopher Faber
- Frits Hein Wapstra
- Thouraya J. Dil
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Universitas Airlangga (ID)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1213/ane.0000000000007701
- Primary Topic
- Intraoperative Neuromonitoring and Anesthetic Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00