Adenoviral Retinitis: A Rare Case Presentation of a Common Virus

HAdV retinitis, though rare, should be considered in immunocompromised patients with progressive necrotising retinitis that is unresponsive to conventional antivirals, particularly when associated with repeatedly negative PCR for herpes viruses, syphilis and <i>Toxoplasma gondii</i>. Intravenous cidofovir may be an effective off-label treatment. A multidisciplinary approach is essential, and serial aqueous PCR is useful for monitoring treatment response.

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Publication Details

Journal
Ocular Immunology and Inflammation
Published
2025-09-05
DOI
https://doi.org/10.1080/09273948.2025.2555379
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Adenoviral Retinitis: A Rare Case Presentation of a Common Virus

Dominic A. Haigh, Emma Davies, Assad Jalil, Shiao Wei Wong et al.
Ocular Immunology and Inflammation
Cytomegalovirus and herpesvirus research
article

Adenoviral Retinitis: A Rare Case Presentation of a Common Virus

Dominic A. Haigh, Emma Davies, Assad Jalil, Shiao Wei Wong, Michael Dennis, Nyaish Mansoor
article en

Abstract

HAdV retinitis, though rare, should be considered in immunocompromised patients with progressive necrotising retinitis that is unresponsive to conventional antivirals, particularly when associated with repeatedly negative PCR for herpes viruses, syphilis and <i>Toxoplasma gondii</i>. Intravenous cidofovir may be an effective off-label treatment. A multidisciplinary approach is essential, and serial aqueous PCR is useful for monitoring treatment response.

Ocular Immunology and InflammationVol. 33(9)
Manchester Royal Eye Hospital (GB), Manchester Royal Infirmary (GB), Manchester University NHS Foundation Trust (GB), The Christie NHS Foundation Trust (GB)
Openalex Percentile: Top 68%
Cytomegalovirus and herpesvirus research
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Adenoviral Retinitis: A Rare Case Presentation of a Common Virus — Dominic A. Haigh, Emma Davies, et al. · Ocular Immunology and Inflammation (2025) | TGRS Research Map | TGRS