Real-world effectiveness of autologous haematopoietic stem cell transplantation for multiple sclerosis in the UK
In this cohort with high EDSS at baseline and including pwPMS, AHSCT led to durable remission of inflammatory activity and stabilisation or improvement of neurological disability, particularly in pwRRMS.
Authors
- Basil Sharrack (ORCID: https://orcid.org/0000-0003-2406-6365)
- Varun Mehra (ORCID: https://orcid.org/0000-0001-6572-0971)
- Ruth Paul
- Ram Malladi (ORCID: https://orcid.org/0000-0002-0242-630X)
- Paolo Antonio Muraro (ORCID: https://orcid.org/0000-0002-3822-1218)
- Richard Nicholas (ORCID: https://orcid.org/0000-0003-0414-1225)
- Alice Mariottini (ORCID: https://orcid.org/0000-0002-1869-7067)
- John A. Snowden (ORCID: https://orcid.org/0000-0001-6819-3476)
- Victoria Potter
- Gavin Brittain (ORCID: https://orcid.org/0000-0002-9903-7203)
- M. Kazmi (ORCID: https://orcid.org/0000-0002-6863-6297)
- Eleonora De Matteis (ORCID: https://orcid.org/0000-0003-3468-3412)
- Rachel Pearce (ORCID: https://orcid.org/0000-0001-8343-2121)
- Maria Pia Sormani (ORCID: https://orcid.org/0000-0001-6892-104X)
- Eli Silber (ORCID: https://orcid.org/0000-0002-3972-0780)
- Olga Ciccarelli (ORCID: https://orcid.org/0000-0001-7485-1367)
- Julia Lee (ORCID: https://orcid.org/0000-0002-4509-6240)
- Alessio Signori
- Ian Gabriel
Institutions
- Imperial College Healthcare NHS Trust (GB)
- Queen Mary University of London (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- National Institute for Health and Care Research (GB)
- Sheffield Teaching Hospitals NHS Foundation Trust (GB)
- King's College Hospital NHS Foundation Trust (GB)
- Ospedale Policlinico San Martino (IT)
- National Hospital for Neurology and Neurosurgery (GB)
- University of Florence (IT)
- University College London (GB)
- Imperial College London (GB)
- University of Genoa (IT)
- University of Sheffield (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1136/jnnp-2025-336755
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94