Hemodynamic Effects of Guideline-Based Sedation in Mechanically Ventilated Adults: A Multicenter Observational Analysis
Propofol-based sedation was associated with clinically significant hemodynamic effects requiring intervention in the early post-intubation period. The marked interpatient variability in hemodynamic responses highlights the importance of personalized management approaches, including risk stratification based on age, sex, and illness severity.
Authors
- Allan J. Walkey (ORCID: https://orcid.org/0000-0003-4685-6894)
- Jiawen Deng (ORCID: https://orcid.org/0000-0002-8274-6468)
- Hemang Yadav (ORCID: https://orcid.org/0000-0002-1889-2524)
- Kiyan Heybati (ORCID: https://orcid.org/0000-0003-4465-2249)
- Ognjen Gajic (ORCID: https://orcid.org/0000-0003-4218-0890)
- Guozhen Xie (ORCID: https://orcid.org/0000-0001-7805-463X)
Institutions
- Boston University (US)
- Mayo Clinic (US)
- University of Toronto (CA)
- University of Michigan (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Critical Care Explorations
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1097/cce.0000000000001313
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00