Design of a High-Precision, Low Temperature Drift Programmable Neural Stimulator

With the rising prevalence of neurological disorders, the demand for precise neuromodulation technologies has increased. Meanwhile, advancements in microelectronics and implantable medical devices have attracted significant attention in clinical treatment and neuroscience. Previous research on neural stimulators has faced challenges such as excessive power consumption, insufficient stimulation precision, and temperature drift, affecting the stability and safety of long-term implantation. This paper proposes a neural stimulator circuit design based on CMOS devices. By adopting a regulated cascode current mirror and an improved Nagata current source, the design achieves low power consumption, high precision, and excellent temperature stability in biphasic current output. To meet the demands of different clinical applications for neural stimulation, a programmable biphasic current control module is developed, allowing flexible adjustment of current amplitude, pulse width, and other timing parameters, thereby reducing tissue damage risks and providing personalized medical solutions. Simulation results demonstrate that the proposed circuit outperforms in output accuracy, energy efficiency, and temperature stability, providing an efficient and safe solution for the application of implantable neural stimulators in neuroscience and clinical treatment.