Lipid Composition Alters Ferroptosis Sensitivity
Changes in lipid composition can affect induction of ferroptosis, explaining why sensitivity of cancer cells in tissue culture does not reliably translate to more complex models and suggesting potential ferroptosis sensitization strategies.
Authors
- Sanjana Singh (ORCID: https://orcid.org/0000-0002-8282-944X)
- Julie J. Purkal (ORCID: https://orcid.org/0000-0001-8429-0313)
- Vivian S. Park (ORCID: https://orcid.org/0009-0006-0975-3190)
- Darren C. Phillips (ORCID: https://orcid.org/0009-0000-6760-9759)
- Sarah Kongpachith (ORCID: https://orcid.org/0000-0002-8462-6881)
- Anlu Chen (ORCID: https://orcid.org/0000-0003-0559-0882)
- Scott J. Dixon (ORCID: https://orcid.org/0000-0001-6230-8199)
- Priya Narayanan (ORCID: https://orcid.org/0000-0002-7020-5007)
- Relja Popovic (ORCID: https://orcid.org/0000-0002-6880-0798)
- Justin P. Ingram (ORCID: https://orcid.org/0009-0009-0152-4811)
- Magdalena B. Murray (ORCID: https://orcid.org/0000-0002-6306-4568)
- Lauren E. Pope (ORCID: https://orcid.org/0000-0002-0335-9356)
- Sha Jin (ORCID: https://orcid.org/0009-0007-7121-5008)
- Grace A. Alchemy (ORCID: https://orcid.org/0000-0002-2173-8878)
- Eli Y. Andino-Frydman (ORCID: https://orcid.org/0009-0008-1741-5604)
Institutions
- Bay Area Air Quality Management District (US)
- Bay Institute (US)
- AbbVie (United States) (US)
- Stanford University (US)
Publication Details
- Journal
- Cancer Research
- Published
- 2025-09-05
- DOI
- https://doi.org/10.1158/0008-5472.can-24-4207
- Citations
- 8
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 7.49