Enhancing Oncology-Specific Question Answering With Large Language Models Through Fine-Tuned Embeddings With Synthetic Data
Our findings highlight the effectiveness of pretrained contextual embeddings and sentence transformers in retrieving pertinent notes from oncology EHRs. The innovative use of LLM-synthesized query-passage pairs for data augmentation was proven to be effective. This fine-tuning approach holds significant promise in specialized fields like health care, where acquiring annotated data is challenging.
Authors
- Zahra Eftekhari
- Chi Wah Wong (ORCID: https://orcid.org/0000-0002-2833-979X)
- Kun‐Han Lu (ORCID: https://orcid.org/0000-0002-0355-8515)
- Allen Mao (ORCID: https://orcid.org/0000-0002-7411-7100)
- Sina Mehdinia
- Kingson Man
Institutions
- City Of Hope National Medical Center (US)
- City of Hope (US)
Publication Details
- Journal
- JCO Clinical Cancer Informatics
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1200/cci-25-00011
- Primary Topic
- Topic Modeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00