Elevated Risk of Postoperative Complications With Non-tobacco Nicotine Use Following Open Reduction and Internal Fixation of Ankle Fractures
NTN use is associated with increased postoperative complications-including infection, wound disruption, nonunion, and malunion-following ORIF for rotational ankle fractures. These findings emphasize the need for further research to guide perioperative risk assessment and improve surgical outcomes.
Authors
- Robert H. Mbilinyi (ORCID: https://orcid.org/0000-0003-2455-0384)
- Jacob R. Zide (ORCID: https://orcid.org/0000-0003-2945-4148)
- Hetsinhji Chavda (ORCID: https://orcid.org/0000-0002-7089-4447)
- William J. Hlavinka (ORCID: https://orcid.org/0009-0006-1018-8395)
- Tarun Sontam (ORCID: https://orcid.org/0009-0005-9756-448X)
- Leonide Toussaint
Institutions
- Baylor University Medical Center (US)
- Ocular Proteomics (United States) (US)
- Centre Alpien de Phytogéographie (CH)
- Universitario Francisco de Asís (UY)
- National Patient Safety Foundation (US)
Publication Details
- Journal
- Journal of the American Academy of Orthopaedic Surgeons
- Published
- 2025-08-29
- DOI
- https://doi.org/10.5435/jaaos-d-25-00714
- Citations
- 3
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 2.42