Study Profile of the Iwate PGS Assessment and Risk Communication (PARC) Study
We collected health information and biospecimens from over 2,000 workers and disclosed the PGS-based ischemic stroke risk. Behavioral effects will be evaluated 1 year after disclosure, with follow-up until 2030. As Japan's first large-scale PGS risk communication study, it will provide initial insights for implementing PGS in personalized preventive medicine.
Authors
- Kazuki Kumada (ORCID: https://orcid.org/0000-0002-2970-7742)
- Satoshi Nagaie (ORCID: https://orcid.org/0000-0002-8152-4556)
- Yuka Kotozaki (ORCID: https://orcid.org/0000-0002-4659-1200)
- Akira Narita (ORCID: https://orcid.org/0000-0002-9076-0710)
- Akimune Fukushima (ORCID: https://orcid.org/0000-0002-6463-1659)
- Shiori Minabe (ORCID: https://orcid.org/0000-0001-7902-925X)
- Akiko Yoshida (ORCID: https://orcid.org/0000-0002-9531-8008)
- Koichi Asahi (ORCID: https://orcid.org/0000-0002-4318-874X)
- Nobuhiro Suzumori (ORCID: https://orcid.org/0000-0001-9003-1289)
- Atsushi Shimizu (ORCID: https://orcid.org/0000-0001-8307-2461)
- Yohei Hamanaka (ORCID: https://orcid.org/0000-0003-4169-7767)
- Yasushi Ishigaki (ORCID: https://orcid.org/0000-0003-2479-5752)
- Yayoi Otsuka‐Yamasaki (ORCID: https://orcid.org/0000-0002-9464-0804)
- Tsuyoshi Hachiya (ORCID: https://orcid.org/0000-0002-5274-3266)
- Masayuki Yamamoto (ORCID: https://orcid.org/0000-0002-9302-5623)
- Atsushi Hasegawa (ORCID: https://orcid.org/0000-0002-9554-2595)
- Soichi Ogishima (ORCID: https://orcid.org/0000-0001-8613-2562)
- Tomoharu Tokutomi
- Mika Sakurai‐Yageta (ORCID: https://orcid.org/0000-0001-5606-3324)
- Hisaaki Kudo (ORCID: https://orcid.org/0000-0002-4477-7095)
- Kozo Tanno (ORCID: https://orcid.org/0000-0002-1264-0684)
- Hideki Ohmomo (ORCID: https://orcid.org/0000-0002-3524-6524)
- Yoichi Sutoh (ORCID: https://orcid.org/0000-0002-1607-9759)
- Yukiko Toya (ORCID: https://orcid.org/0000-0001-8461-9203)
- Fuji Nagami (ORCID: https://orcid.org/0000-0002-3652-9788)
- Shohei Komaki (ORCID: https://orcid.org/0000-0002-0486-3239)
- Makoto Sasaki (ORCID: https://orcid.org/0000-0002-3108-4361)
- Ryujin Endo
Institutions
- Iwate Medical University (JP)
- Tohoku University (JP)
- Tohoku Medical Megabank Organization (JP)
Publication Details
- Journal
- Journal of Epidemiology
- Published
- 2025-09-05
- DOI
- https://doi.org/10.2188/jea.je20250078
- Primary Topic
- Data-Driven Disease Surveillance
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development