A Case Study on the Diagnostic Complexity of Krukenberg Tumor in Pregnancy: Clinical Insights and Management

Krukenberg tumors, metastatic ovarian carcinomas primarily originating from gastrointestinal malignancies, present significant diagnostic and therapeutic challenges during pregnancy. We report a case of a 39-year-old pregnant woman initially diagnosed with autoimmune pancreatitis (AIP) and cholestasis of pregnancy, later found to have metastatic signet ring cell carcinoma of the stomach with ovarian involvement. This case highlights the complexities in differentiating malignancy from benign hepatobiliary disorders during pregnancy, emphasizing the need for a multidisciplinary approach. Early integration of tumor markers, advanced imaging, and HISORt criteria can facilitate timely diagnosis and improve clinical outcomes.

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Publication Details

Journal
Case Reports in Clinical Practice
Published
2025-09-05
DOI
https://doi.org/10.18502/crcp.v10i1.19477
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
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article

A Case Study on the Diagnostic Complexity of Krukenberg Tumor in Pregnancy: Clinical Insights and Management

Leila Mousavi Seresht, Azam Zafabakhsh, Shirin Souri, Sheyda Riyahi
Case Reports in Clinical Practice
Cancer Risks and Factors
article

A Case Study on the Diagnostic Complexity of Krukenberg Tumor in Pregnancy: Clinical Insights and Management

Leila Mousavi Seresht, Azam Zafabakhsh, Shirin Souri, Sheyda Riyahi
article en

Abstract

Krukenberg tumors, metastatic ovarian carcinomas primarily originating from gastrointestinal malignancies, present significant diagnostic and therapeutic challenges during pregnancy. We report a case of a 39-year-old pregnant woman initially diagnosed with autoimmune pancreatitis (AIP) and cholestasis of pregnancy, later found to have metastatic signet ring cell carcinoma of the stomach with ovarian involvement. This case highlights the complexities in differentiating malignancy from benign hepatobiliary disorders during pregnancy, emphasizing the need for a multidisciplinary approach. Early integration of tumor markers, advanced imaging, and HISORt criteria can facilitate timely diagnosis and improve clinical outcomes.

Case Reports in Clinical Practice
Isfahan University of Medical Sciences (IR)
Openalex Percentile: Top 67%
Cancer Risks and Factors
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A Case Study on the Diagnostic Complexity of Krukenberg Tumor in Pregnancy: Clinical Insights and Management — Leila Mousavi Seresht, Azam Zafabakhsh, et al. · Case Reports in Clinical Practice (2025) | TGRS Research Map | TGRS