Micronutrient dynamics and deficiency risk across pregnancy and postpartum in a Slovak cohort
Our findings reveal significant differences in maternal micronutrient levels across pregnancy and postpartum. While some nutrients, including vitamin D and folate, remained relatively stable, others such as vitamin A, B12, iron and zinc were observed at lower levels, and vitamin E at higher levels during pregnancy. Vitamin E levels in the 3rd trimester frequently exceeded reference values for the general adult population, whereas zinc levels were significantly lower postpartum. We observed high prevalence of vitamin B12 and iron deficiencies, as indicated by transferrin saturation, particularly in the 3rd trimester. Vitamin D deficiency was prevalent throughout pregnancy and postpartum. Finally, our analysis demonstrated that dried blood spot (DBS) technology provides comparable results to venous blood analysis for measuring vitamin A, D and homocysteine levels.
Authors
- Neha Basheer (ORCID: https://orcid.org/0000-0003-3669-3825)
- Alexandra Krištúfková (ORCID: https://orcid.org/0000-0002-1216-0824)
- Michal Fresser
- Norbert Žilka (ORCID: https://orcid.org/0000-0003-2397-2083)
- Katarina Koprdova
- Matus Lieskovsky
Institutions
- Slovak Academy of Sciences (SK)
- Slovak National Museum (SK)
- University Hospital Bratislava (SK)
- Institute of Neuroimmunology of the Slovak Academy of Sciences (SK)
- University of Ss. Cyril and Methodius in Trnava (SK)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1371/journal.pone.0331125
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00