Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body

Hematogenous metastases of hepatocellular carcinoma (HCC) to the small intestine are rare. In most cases, hematogenous metastasis is symptomatic, including perforation or bleeding, and the prognosis is poor. A 63-year-old man had lower right abdominal pain, and small intestinal obstruction due to chronic inflammation of the foreign body was suspected on computed tomography. Blood tests revealed elevated alpha-fetoprotein (AFP). He had undergone four surgeries for HCC. Conservative treatment was administered, but there was little improvement. A segmental resection of the small intestine was performed. A type 2 tumor was found in the resected specimen, and pathological examination led to a diagnosis of HCC metastasis in the small intestine. He survived without recurrence for 10 months after surgery. When a patient with a history of HCC treatment develops intestinal obstruction or intussusception, it is necessary to consider the possibility of small intestinal metastasis, especially if there is an increase in AFP.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-08-13
DOI
https://doi.org/10.1093/jscr/rjaf679
Primary Topic
Metastasis and carcinoma case studies
Type
article
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article

Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body

Hideya Takeuchi, Shohei Yoshiya, Kazuhiro Tada, Hidenori Koso et al.
Journal of Surgical Case Reports
Metastasis and carcinoma case studies
article

Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body

Hideya Takeuchi, Shohei Yoshiya, Kazuhiro Tada, Hidenori Koso, Kentaro Iwaki, Kengo Fukuzawa, Tomoharu Yoshizumi, I Kawada, Fumitaka Yoshizumi, Yosuke Kuroda, Kensaku Ito, Shotaro Nakamura, Yo-ichi Yamashita, Shoji Hiroshige, Masakazu Matsuda
article en

Abstract

Hematogenous metastases of hepatocellular carcinoma (HCC) to the small intestine are rare. In most cases, hematogenous metastasis is symptomatic, including perforation or bleeding, and the prognosis is poor. A 63-year-old man had lower right abdominal pain, and small intestinal obstruction due to chronic inflammation of the foreign body was suspected on computed tomography. Blood tests revealed elevated alpha-fetoprotein (AFP). He had undergone four surgeries for HCC. Conservative treatment was administered, but there was little improvement. A segmental resection of the small intestine was performed. A type 2 tumor was found in the resected specimen, and pathological examination led to a diagnosis of HCC metastasis in the small intestine. He survived without recurrence for 10 months after surgery. When a patient with a history of HCC treatment develops intestinal obstruction or intussusception, it is necessary to consider the possibility of small intestinal metastasis, especially if there is an increase in AFP.

Journal of Surgical Case ReportsVol. 2025(9)
Kyushu University (JP), Oita Red Cross Hospital (JP)
Openalex Percentile: Top 66%
Metastasis and carcinoma case studies
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