[A case of multiple organ dysfunction caused by acute glyphosate combined with alcohol poisoning].

This study analyzes the clinical data of a patient presenting with acute poisoning following the co-ingestion of a pesticide (approximately 100-120 ml of 41% glyphosate-isopropylammonium) and alcohol (approximately 100 g of ethanol). The patient developed multiple organ dysfunction syndrome (MODS), manifesting as acute kidney injury (AKI), metabolic acidosis, hyperkalemia, acute lung injury (ALI), acute liver injury, acute intestinal injury, and systemic inflammatory response syndrome (SIRS). Following administration of general supportive care combined with continuous renal replacement therapy (CRRT) and hemoperfusion (HP), the patient recovered fully and was discharged. Acute combined glyphosate and ethanol poisoning can induce MODS. Analysis of this patient's diagnosis and treatment process enhances clinicians' understanding of this toxicological presentation and offers valuable clinical insights to improve survival rates in similar cases.

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Publication Details

Journal
PubMed
Published
2025-08-20
DOI
https://doi.org/10.3760/cma.j.cn121094-20240520-00229
Primary Topic
Pesticide and Herbicide Environmental Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

[A case of multiple organ dysfunction caused by acute glyphosate combined with alcohol poisoning].

Guyu Li, Nateiya Yongolo, Wuxiang Xie, Yue Qiu
PubMed
Pesticide and Herbicide Environmental Studies
article

[A case of multiple organ dysfunction caused by acute glyphosate combined with alcohol poisoning].

Guyu Li, Nateiya Yongolo, Wuxiang Xie, Yue Qiu
article en

Abstract

This study analyzes the clinical data of a patient presenting with acute poisoning following the co-ingestion of a pesticide (approximately 100-120 ml of 41% glyphosate-isopropylammonium) and alcohol (approximately 100 g of ethanol). The patient developed multiple organ dysfunction syndrome (MODS), manifesting as acute kidney injury (AKI), metabolic acidosis, hyperkalemia, acute lung injury (ALI), acute liver injury, acute intestinal injury, and systemic inflammatory response syndrome (SIRS). Following administration of general supportive care combined with continuous renal replacement therapy (CRRT) and hemoperfusion (HP), the patient recovered fully and was discharged. Acute combined glyphosate and ethanol poisoning can induce MODS. Analysis of this patient's diagnosis and treatment process enhances clinicians' understanding of this toxicological presentation and offers valuable clinical insights to improve survival rates in similar cases.

PubMedVol. 43(8)
The First People's Hospital of Guiyang (CN)
Openalex Percentile: Top 82%
Pesticide and Herbicide Environmental Studies
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[A case of multiple organ dysfunction caused by acute glyphosate combined with alcohol poisoning]. — Guyu Li, Nateiya Yongolo, et al. · PubMed (2025) | TGRS Research Map | TGRS