Arachidonic acid fuels inflammation by unlocking macrophage protein phosphatase 5 after myocardial infarction

The findings elucidate the conserved role of 5-lipoxygenase phosphorylation regulated LTB4 levels in MI and identify PP5 as a potential therapeutic target for the treatment of MI.

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Publication Details

Journal
European Heart Journal
Published
2025-06-24
DOI
https://doi.org/10.1093/eurheartj/ehaf493
Citations
4
Primary Topic
Macrophage Migration Inhibitory Factor
Type
article
Field-Weighted Citation Impact
3.19
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article

Arachidonic acid fuels inflammation by unlocking macrophage protein phosphatase 5 after myocardial infarction

Hongfeng Jiang, Lei Shi, Dao Wen Wang, Zhong Xian et al.
4 citations
European Heart Journal
Macrophage Migration Inhibitory Factor
3.19
article

Arachidonic acid fuels inflammation by unlocking macrophage protein phosphatase 5 after myocardial infarction

Hongfeng Jiang, Lei Shi, Dao Wen Wang, Zhong Xian, Xilin Shen, Chen Chen, Ting Zhou, Wenbin Cai, Hongxi Yang, Ding Ai, Zhipeng Chen, Qiang Liu, Mingming Liu, Yan Zhang, Jianping Li, Fangfang Fan, Suli Feng, Haoyu Weng, Jiawei Song, Mulin Jun Li
article en
4 citations

Abstract

The findings elucidate the conserved role of 5-lipoxygenase phosphorylation regulated LTB4 levels in MI and identify PP5 as a potential therapeutic target for the treatment of MI.

European Heart JournalVol. 47(4)
Capital Medical University (CN), Peking University (CN), Tianjin Medical University General Hospital (CN), Tianjin Medical University Cancer Institute and Hospital (CN), Beijing Anzhen Hospital (CN), Peking University First Hospital (CN), Second Hospital of Tianjin Medical University (CN), Tongji Hospital (CN), Huazhong University of Science and Technology (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 7%
Macrophage Migration Inhibitory Factor
3.19
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