Case Report: SARS-CoV-2-associated immune dysfunction manifesting as concurrent fulminant type 1 diabetes mellitus and subacute thyroiditis

This case suggests that SARS-CoV-2 may induce dual-gland damage through immune injury mediated by angiotensin-converting enzyme 2 receptor and cytokine storms. Clinicians should be vigilant for acute hyperglycemia and neck pain following SARS-CoV-2 infection. Serial monitoring of blood glucose and thyroid-related parameters is essential as early intervention may improve prognosis.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-08-18
DOI
https://doi.org/10.3389/fmed.2025.1644656
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: SARS-CoV-2-associated immune dysfunction manifesting as concurrent fulminant type 1 diabetes mellitus and subacute thyroiditis

Hongxia Zhu, Jie Xu, Lian Zhong, Fang Wei et al.
Frontiers in Medicine
COVID-19 Clinical Research Studies
article

Case Report: SARS-CoV-2-associated immune dysfunction manifesting as concurrent fulminant type 1 diabetes mellitus and subacute thyroiditis

Hongxia Zhu, Jie Xu, Lian Zhong, Fang Wei, Huanping Wang
article en

Abstract

This case suggests that SARS-CoV-2 may induce dual-gland damage through immune injury mediated by angiotensin-converting enzyme 2 receptor and cytokine storms. Clinicians should be vigilant for acute hyperglycemia and neck pain following SARS-CoV-2 infection. Serial monitoring of blood glucose and thyroid-related parameters is essential as early intervention may improve prognosis.

Frontiers in MedicineVol. 12
Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 71%
COVID-19 Clinical Research Studies
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