Novel mutations associated with clofazimine resistance in <i>Mycobacterium intracellulare</i>

This work highlights marR as a key determinant of clofazimine resistance in M. intracellulare and underscores the need for further mechanistic studies with implications for rapid molecular detection and effective treatment.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-08-18
DOI
https://doi.org/10.1093/jac/dkaf321
Primary Topic
Mycobacterium research and diagnosis
Type
article
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article

Novel mutations associated with clofazimine resistance in Mycobacterium intracellulare

Yuwei Qiu, Dan Cao, Xu Dong, Pusheng Xu et al.
Journal of Antimicrobial Chemotherapy
Mycobacterium research and diagnosis
article

Novel mutations associated with clofazimine resistance in Mycobacterium intracellulare

Yuwei Qiu, Dan Cao, Xu Dong, Pusheng Xu, Kaijin Xu, Ying Zhang, Li Yi, Xiuzhi Jiang, Yanghui Xiang, Xin Yuan
article en

Abstract

This work highlights marR as a key determinant of clofazimine resistance in M. intracellulare and underscores the need for further mechanistic studies with implications for rapid molecular detection and effective treatment.

Journal of Antimicrobial ChemotherapyVol. 80(11)
National Centre for Infectious Diseases (SG), Shandong First Medical University (CN), Zhejiang University (CN)
Openalex Percentile: Top 68%
Mycobacterium research and diagnosis
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Novel mutations associated with clofazimine resistance in <i>Mycobacterium intracellulare</i> — Yuwei Qiu, Dan Cao, et al. · Journal of Antimicrobial Chemotherapy (2025) | TGRS Research Map | TGRS