Chronic kidney disease from non-traditional causes: report from the fourth international workshop

Objective: Chronic kidney disease of nontraditional cause (CKDnt) is a significant concern in Mesoamerica and South Asia.Despite research progress, its causes remain unclear and disease burden high.The international workshop was convened to evaluate current evidence and guide public health strategies.Materials and methods: The Fourth International Workshop on CKDnt was held in 2024 and organized by the Consortium for the Epidemic of Nephropathy in Central America and Mexico (CENCAM), in collaboration with the Executive Secretariat of the Council of Ministers of Health of Central America and the Dominican Republic (SE-COMISCA), the Latin American Society of Nephrology and Hypertension (SLANH), the Central American Program for Health, Work and Environment (SALTRA), and the Spanish Agency for International Development Cooperation (AECID).The objective was to provide evidence-based support for the program "Strategy for the Prevention, Mitigation, and Control of CKDnt in Central America and the Dominican Republic".Results: Participants numbered 165, most from Mesoamerica.Workshop discussions were centered around: (1) the causes of CKDnt, (2) methodological research approaches, and (3) strategies for application of findings.Conclusions: Addressing CKDnt requires coordinated, evidence-based actions at both regional and international levels.