Early Biomechanical Alterations in Granular Corneal Dystrophy Type 2 From p.Ala546Asp Mutation Carriers
The p.Ala546Asp mutation may be associated with early corneal biomechanical instability, regardless of visible deposits. These findings suggest that biomechanical assessment may aid in the description of subclinical corneal changes in GCD2 and contribute to a better understanding of biomechanical variability among mutation carriers.
Authors
- Arturo Ramírez-Miranda (ORCID: https://orcid.org/0000-0001-6419-5116)
- Guillermo Raúl Vera-Duarte (ORCID: https://orcid.org/0000-0002-3417-256X)
- Leire Irusteta
- Enrique O Graue-Hernández (ORCID: https://orcid.org/0000-0003-3267-3915)
- Alejandro Navas (ORCID: https://orcid.org/0000-0002-9417-5711)
- Jorge Luis Domene-Hickman
- Luis Haro-Morlett (ORCID: https://orcid.org/0000-0002-4272-6497)
Institutions
- Ocular Proteomics (United States) (US)
Publication Details
- Journal
- Cornea
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1097/ico.0000000000003981
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00