Management of significant pleural effusion at ovarian cancer diagnosis: Outcomes of triage to neoadjuvant chemotherapy without thoracic assessment

Limited evidence directs the best management for patients presenting with clinical Stage IVA disease. Our data represent a particularly high-risk subgroup which may be characteristic of patients with large pleural effusions and adds important information showing that approximately half of these patients have ≥2 indications to favor NACT, signifying their high-risk status. Despite this, when CGR in the abdomen was achieved at IDS, median OS was greater than 5 years.

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Publication Details

Journal
Gynecologic Oncology Reports
Published
2025-09-04
DOI
https://doi.org/10.1016/j.gore.2025.101944
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Management of significant pleural effusion at ovarian cancer diagnosis: Outcomes of triage to neoadjuvant chemotherapy without thoracic assessment

Conway Xu, Matthew Stephen Block, Carrie Langstraat, Kelly H. Bruce et al.
Gynecologic Oncology Reports
Ovarian cancer diagnosis and treatment
article

Management of significant pleural effusion at ovarian cancer diagnosis: Outcomes of triage to neoadjuvant chemotherapy without thoracic assessment

Conway Xu, Matthew Stephen Block, Carrie Langstraat, Kelly H. Bruce, Chiara Ainio, Stuart A. Ostby, William A. Cliby, Amanika Kumar
article en

Abstract

Limited evidence directs the best management for patients presenting with clinical Stage IVA disease. Our data represent a particularly high-risk subgroup which may be characteristic of patients with large pleural effusions and adds important information showing that approximately half of these patients have ≥2 indications to favor NACT, signifying their high-risk status. Despite this, when CGR in the abdomen was achieved at IDS, median OS was greater than 5 years.

Gynecologic Oncology ReportsVol. 61
Mayo Clinic (US), Mayo Clinic in Arizona (US)
Openalex Percentile: Top 69%
Ovarian cancer diagnosis and treatment
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