Efficacy of Rituximab as Adjunctive Therapy to Immunosuppressive Agents in Adult Primary Focal Segmental Glomerulosclerosis

RTX shows promise in treating primary FSGS, particularly in steroid-dependent patients, those with less severe nephrotic syndrome, and previous responders. RTX offers durable responses for most patients, but long-term management remains challenging in those who relapse and need retreatment.

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Publication Details

Journal
Kidney International Reports
Published
2025-09-04
DOI
https://doi.org/10.1016/j.ekir.2025.08.046
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy of Rituximab as Adjunctive Therapy to Immunosuppressive Agents in Adult Primary Focal Segmental Glomerulosclerosis

Rabeh Khairy Saleh, Shereen Mohammed Mohammed Elsaghir, Thekra Mohamed, Basma Fathy et al.
Kidney International Reports
Renal Diseases and Glomerulopathies
article

Efficacy of Rituximab as Adjunctive Therapy to Immunosuppressive Agents in Adult Primary Focal Segmental Glomerulosclerosis

Rabeh Khairy Saleh, Shereen Mohammed Mohammed Elsaghir, Thekra Mohamed, Basma Fathy, Esmat Fathi, Rasha Nazih Yousef, Nicolas Toni, A. M. S. Mahdy, S. Abdelrazek, Ayman Ahmed Abd Rabou, Osama Mohamed, Manar M. Sayed, Mohamed Ahmed Abdelsamie, H. M. Mohammed, Aml Azzam, Marwa Ibrahim Mohamed, Reem Y Abdelazeem Elgarhy
article en

Abstract

RTX shows promise in treating primary FSGS, particularly in steroid-dependent patients, those with less severe nephrotic syndrome, and previous responders. RTX offers durable responses for most patients, but long-term management remains challenging in those who relapse and need retreatment.

Kidney International ReportsVol. 10(11)
Minia University (EG)
Openalex Percentile: Top 74%
Renal Diseases and Glomerulopathies
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