Early Clinical Outcomes of Cultured Human Corneal Endothelial Cell Injection (Vyznova) for Bullous Keratopathy: Initial Clinical Experience

Vyznova therapy seems to be effective in restoring corneal clarity in patients with BK. This real-world experience underscores the feasibility of implementing cHCEC injections in institutions beyond the developer sites. Careful intraoperative management is necessary to avoid complications, such as detachment of Descemet membrane.

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Publication Details

Journal
Cornea
Published
2025-09-03
DOI
https://doi.org/10.1097/ico.0000000000003984
Citations
1
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
1.36
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article

Early Clinical Outcomes of Cultured Human Corneal Endothelial Cell Injection (Vyznova) for Bullous Keratopathy: Initial Clinical Experience

Takefumi Yamaguchi, Hideaki Yokogawa, Yukari Yagi-Yaguchi, Natsuko Mori et al.
1 citations
Cornea
Corneal surgery and disorders
1.36
article

Early Clinical Outcomes of Cultured Human Corneal Endothelial Cell Injection (Vyznova) for Bullous Keratopathy: Initial Clinical Experience

Takefumi Yamaguchi, Hideaki Yokogawa, Yukari Yagi-Yaguchi, Natsuko Mori, Akira Kobayashi, Seiichiro Sugita, Tomomi Higashide
article en
1 citations

Abstract

Vyznova therapy seems to be effective in restoring corneal clarity in patients with BK. This real-world experience underscores the feasibility of implementing cHCEC injections in institutions beyond the developer sites. Careful intraoperative management is necessary to avoid complications, such as detachment of Descemet membrane.

Cornea
Kanazawa University (JP), Tokyo Dental College Ichikawa General Hospital (JP), Miyake Eye Hospital (JP)
Openalex Percentile: Top 16%
Corneal surgery and disorders
1.36
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