Purified Cucurbitacin D Leads to Alterations of Apoptotic and Autophagic Genes Expression in MDA‐MB‐468 and MCF‐7 Human Breast Cancer Cells

Our results confirmed that CuD may influence breast cancer cell lines' viability at specific doses and by altering the expression of these genes. The differences between the gene's aberrations in our breast cancer cell lines propose that these genes can have a distinct role in the pathophysiology and therapy responsiveness of various subtypes of breast cancer.